PHS 734 - Proteomics

This course will deal with the general principles, applications and current advances in the field of proteomics (protein expression profiling under normal and disease state). The students in this course will gain knowledge in the fundamental concepts in protein chemistry and hands-on experience in protein isolation, separation, and characterization including post-translational modification. This course will prepare students in project design, selection of various analytical tools; 2DE electrophoresis, differential in gel electrophoresis (DIGE), N-terminal protein sequencing, mass spectrometry platforms (MALDI-TOF, ESI-TOF) and interpreting tandem mass spectrometry data. (Offered as needed.) 3 credits