PHS 736 - Pharmacology of Anti-Cancer Agents

This course provides a detailed overview of the pharmacology of conventional, targeted and immunoregulatory antineoplastic agents. Molecular mechanisms of action of the various drug classes along with established mechanisms of resistance will be discussed. The focus of learning is on the use of in-vitro and in-vivo models in antineoplastic drug discovery and in understanding the underlying mechanisms of cytotoxicity and resistance through journal club discussions, assigned readings and peer presentations. (Offered as needed.) 2 credits